Az utóbbi évek tudományos közleményei
2024
Poór Miklós, Dombi Ágnes, Fliszár-Nyúl Eszter, Pedroni Lorenzo, Dellafiora Luca: Effect of Chrysin and Chrysin-7-sulfate on Ochratoxin A-Albumin Interaction and ont he Plasma and Kidney of the Mycotoxin in Rats, ACS OMEGA 9: 15 PP. 17655-17666., 12 p., (2024)
https://doi.org/10.1021/acsomega.4c01738
Göntér K., Dombi Á., Kormos V., Pintár E., Pozsgai G.: Examination of Effect of Dimethyl Trisulfide in Acute Stress Mouse Model with the Potential Involvement of TRPA1 Ion Channel, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25: 14 Paper: 7701, 22 p. (2024)
https://doi.org/10.3390/ijms25147701
Hudhud, Lina ; Szőke, Éva ; Bencze, Noémi ; Pohóczky, Krisztina ; Helyes, Zsuzsanna
Transient Receptor Potential (TRP) channels in cancer: Implications for drug discovery and development. In: Szallasi, Árpád (szerk.) TRP Channels as Therapeutic Targets : Advances in Basic Science and Clinical Use. Waltham (MA), Amerikai Egyesült Államok : Elsevier Academic Press (2024) pp. 387-401., 15 p.
https://doi.org/10.1016/B978-0-443-18653-0.00003-4
Lina Hudhud, Katalin Rozmer, Angéla Kecskés, Krisztina Pohóczky, Noémi Bencze, Krisztina Buzás, Éva Szőke, Zsuzsanna Helyes: Transient Receptor Potential Ankyrin 1 Ion Channel Is Expressed in Osteosarcoma and Its Activation Reduces Viability. Int. J. Mol. Sci. 2024, 25(7), 3760;
https://doi.org/10.3390/ijms25073760
Kaci, Hana ; Dombi, Ágnes ; Gömbös, Patrik ; Szabó, András ; Bakos, Éva ; Özvegy-Laczka, Csilla ; Poór, Miklós, Interaction of mycotoxins zearalenone, α-zearalenol, and β-zearalenol with cytochrome P450 (CYP1A2, 2C9, 2C19, 2D6, and 3A4) enzymes and organic anion transporting polypeptides (OATP1A2, OATP1B1, OATP1B3, and OATP2B1), TOXICOLOGY IN VITRO 96 Paper: 105789 , 8 p. (2024)
https://doi.org/10.1016/j.tiv.2024.105789
2023
Orján, Erik Márk ; Kormányos, Eszter Sára ; Fűr, Gabriella Mihalekné ; Dombi, Ágnes ; Bálint, Emese Réka ; Balla, Zsolt ; Balog, Beáta Adél ; Dágó, Ágnes ; Totonji, Ahmad ; Bátai, Zoárd István et al., The anti-inflammatory effect of dimethyl trisulfide in experimental acute pancreatitis. SCIENTIFIC REPORTS 13 : 1 Paper: 16813 , 19 p. (2023)
https://doi.org/10.1038/s41598-023-43692-9
Balázs, Orsolya ; Dombi, Ágnes ; Zsidó, Balázs Z ; Hetényi, Csaba ; Valentová, Kateřina ; Vida, Róbert G ; Poór, Miklós, Inhibition of xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation by luteolin, naringenin, myricetin, ampelopsin and their conjugated metabolites. BIOMEDICINE & PHARMACOTHERAPY 167 Paper: 115548 , 10 p. (2023)
https://doi.org/10.1016/j.biopha.2023.115548
Tamás Hlogyik, Réka Laczkó-Rigó, Éva Bakos, Miklós Poór, Zoltán Kele, Csilla Özvegy-Laczka, Erzsébet Mernyák, Synthesis and in vitro photodynamic activity of aza-BODIPY-based photosensitizers. Organic & Biomolecular Chemistry 21 (2023) 6018.
https://doi.org/10.1039/d3ob00699a
Zsolt Csenki, Tibor Bartók, Illés Bock, Levente Horváth, Beáta Lemli, Balázs Zoltán Zsidó, Cserne Angeli, Csaba Hetényi, István Szabó, Béla Urbányi, Melinda Kovács, Miklós Poór, Interaction of fumonisin B1, N-palmitoyl-fumonisin B1, 5-O-palmitoyl-fumonisin B1, and fumonisin B4 mycotoxins with human serum albumin and their toxic impacts on zebrafish embryos. Biomolecules 13 (2023) 755.
https://doi.org/10.3390/biom13050755
Orsolya Balázs, Ágnes Dombi, Balázs Z. Zsidó, Csaba Hetényi, Róbert G. Vida, Miklós Poór, Probing the interactions of 31 mycotoxins with xanthine oxidase: Alternariol, alternariol-3-sulfate and α-zearalenol are allosteric inhibitors of the enzyme. Toxins 15 (2023) 250.
https://doi.org/10.3390/toxins15040250
Miklós Poór, Beáta Lemli, Péter Vilmányi, Ágnes Dombi, Zoltán Nagymihály, Eszter Borbála Both, Nándor Lambert, Tamás Czömpöly, Lajos Szente, Probing serum albumins and cyclodextrins as binders of the mycotoxin metabolites alternariol-3-glucoside, alternariol-9-monomethylether-3-glucoside, and zearalenone-14-glucuronide. Metabolites 13 (2023) 446.
https://doi.org/10.3390/metabo13030446
Rita Börzsei, Éva Borbély, Boglárka Kántás, Lina Hudhud, Ádám Horváth, Éva Szőke, Csaba Hetényi, Zsuzsanna Helyes, Erika Pintér, The heptapeptide somatostatin analogue TT-232 exerts analgesic and anti-inflammatory actions via SST4 receptor activation: In silico, in vitro and in vivo evidence in mice. Biochemical Pharmacology 209 (2023) 115419.
https://doi.org/10.1016/j.bcp.2023.115419
Eszter Fliszár-Nyúl, John-Lewis Zinia Zaukuu, Lajos Szente, Zoltán Kovács, Miklós Poór, Impacts of β-cyclodextrin bead polymer (BBP) treatment on the quality of red and white wines: Color, polyphenol content, and electronic tongue analysis. LWT - Food Science and Technology 176 (2023) 114567.
https://doi.org/10.1016/j.lwt.2023.114567
Eszter Fliszár-Nyúl, Orsolya Ungvári, Ágnes Dombi, Csilla Özvegy-Laczka, Miklós Poór, Interactions of mycotoxin alternariol with cytochrome P450 enzymes and OATP transporters. Metabolites 13 (2023) 45.
https://doi.org/10.3390/metabo13010045
Hana Kaci, Slávka Bodnárová, Eszter Fliszár-Nyúl, Beáta Lemli, Helena Pelantová, Kateřina Valentová, Éva Bakos, Csilla Özvegy-Laczka, Miklós Poór, Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters. Biomedicine & Pharmacotherapy 157 (2023) 114078.
https://doi.org/10.1016/j.biopha.2022.114078
Erika Pintér, Zsuzsanna Helyes, Éva Szőke, Kata Bölcskei, Angéla Kecskés, Gábor Pethő, The triple function of the capsaicin-sensitive sensory neurons: In memoriam János Szolcsányi. Temperature 10 (2023) 13-34.
https://doi.org/10.1080/23328940.2022.2147388
Fruzsina Kiss, Krisztina Pohóczky, Anikó Görbe, Fanni Dembrovszky, Szabolcs Kiss, Péter Hegyi, Lajos Szakó, Lilla Tóth, Éva Somogyiné Ezer, Eszter Szalai, Zsuzsanna Helyes, Addition of EGFR inhibitors to standard chemotherapy increases survival of advanced head and neck squamous cell carcinoma patients: a systematic review and meta-analysis. Oral Diseases 29 (2023) 1905-1919.
https://doi.org/10.1111/odi.14228
2022
Ádám Horváth, János Erostyák, Éva Szőke, Effect of Lipid Raft Disruptors on Cell Membrane Fluidity Studied by Fluorescence Spectroscopy. International Journal of Molecular Sciences 23 (2022) 13729.
https://doi.org/10.3390/ijms232213729
Beáta Lemli, Péter Vilmányi, Eszter Fliszár-Nyúl, Balázs Z. Zsidó, Csaba Hetényi, Lajos Szente, Miklós Poór, Testing serum albumins and cyclodextrins as potential binders of the mycotoxin metabolites alternariol-3-sulfate, alternariol-9-monomethylether, and alternariol-9-monomethylether-3-sulfate. International Journal of Molecular Sciences 23 (2022) 14353.
https://doi.org/10.3390/ijms232214353
Beáta Lemli, Zuzana Lomozová, Tamás Huber, András Lukács, Miklós Poór, Effects of Heme site (FA1) ligands bilirubin, biliverdin, hemin, and methyl orange on the albumin binding of Site I marker warfarin: Complex allosteric interactions. International Journal of Molecular Sciences 23 (2022) 14007.
https://doi.org/10.3390/ijms232214007
Zsuzsanna Szőke, Bianka Babarczi, Miklós Mézes, István Lakatos, Miklós Poór, Eszter Fliszár-Nyúl, Miklós Oldal, Árpád Czéh, Kornélia Bodó, György Nagyéri, Szilamér Ferenczi, Analysis and Comparison of Rapid Methods for the Determination of Ochratoxin A Levels in Organs and Body Fluids Obtained from Exposed Mice. Toxins 14 (2022) 634.
https://doi.org/10.3390/toxins14090634
Eszter Fliszár-Nyúl, Rita Csepregi, Gábor Benkovics, Lajos Szente, Miklós Poór, Testing the Protective Effects of Sulfobutylether-Beta-Cyclodextrin (SBECD) and Sugammadex against Chlorpromazine-Induced Acute Toxicity in SH-SY5Y Cell Line and in NMRI Mice. Pharmaceutics 14 (2022) 1888.
https://doi.org/10.3390/pharmaceutics14091888
Eszter Fliszár-Nyúl, Illés Bock, Rita Csepregi, Lajos Szente, István Szabó, Zsolt Csenki, Miklós Poór, Testing the protective effects of cyclodextrins vs. alternariol-induced acute toxicity in HeLa cells and in zebrafish embryos. Environmental Toxicology and Pharmacology 95 (2022) 103965.
https://doi.org/10.1016/j.etap.2022.103965
Eszter Fliszár-Nyúl, Zelma Faisal, Renáta Skaper, Beáta Lemli, Bayarsaikhan Bayartsetseg, Csaba Hetényi, Patrik Gömbös, András Szabó, Miklós Poór, Interaction of the Emerging Mycotoxins Beauvericin, Cyclopiazonic Acid, and Sterigmatocystin with Human Serum Albumin. Biomolecules 12 (2022) 1106.
https://doi.org/10.3390/biom12081106
Krisztina Pohóczky, József Kun, Nikolett Szentes, Tímea Aczél, Péter Urbán, Attila Gyenesei, Kata Bölcskei, Éva Szőke, Serena Sensi, Ádám Dénes, Andreas Goebel, Valéria Tékus, Zsuzsanna Helyes, Discovery of novel targets in a complex regional pain syndrome mouse model by transcriptomics: TNF and JAK-STAT pathways. Pharmacological Research 182 (2022) 106347.
https://doi.org/10.1016/j.phrs.2022.106347
Miklós Poór, Hana Kaci, Slávka Bodnárová, Violetta Mohos, Eszter Fliszár-Nyúl, Sándor Kunsági-Máté, Csilla Özvegy-Laczka, Beáta Lemli, Interactions of resveratrol and its metabolites (resveratrol-3-sulfate, resveratrol-3-glucuronide, and dihydroresveratrol) with serum albumin, cytochrome P450 enzymes, and OATP transporters. Biomedicine & Pharmacotherapy 151 (2022) 113136.
https://doi.org/10.1016/j.biopha.2022.113136
Erzsébet Pászti-Gere, Anna Szentkirályi-Tóth, Pál Szabó, Torsten Steinmetzer, Eszter Fliszár-Nyúl, Miklós Poór, In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity. Biomedicine & Pharmacotherapy 151 (2022) 113124.
https://doi.org/10.1016/j.biopha.2022.113124
Lina Hudhud, David R. Chisholm, Andrew Whiting, Anita Steib, Krisztina Pohóczky, Angéla Kecskés, Éva Szőke, Zsuzsanna Helyes, Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without Altering Viability. Molecules 27 (2022) 977.
https://doi.org/10.3390/molecules27030977
Fruzsina Kiss, Viktória Kormos, Éva Szőke, Angéla Kecskés, Norbert Tóth, Anita Steib, Árpád Szállási, Bálint Scheich, Balázs Gaszner, József Kun, Gábor Fülöp, Krisztina Pohóczky, Zsuzsanna Helyes, Functional Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Ion Channels Are Overexpressed in Human Oral Squamous Cell Carcinoma. International Journal of Molecular Sciences 23 (2022) 1921.
https://doi.org/10.3390/ijms23031921
Erzsébet Pászti-Gere, Anna Szentkirályi, Zsófia Fedor, Gábor Nagy, Zoltán Szimrók, Zoltán Pászti, Anna Pászti, Oliver Pilgram, Torsten Steinmetzer, Slávka Bodnárová, Eszter Fliszár-Nyúl, Miklós Poór, In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P450 isoenzymes. Biomedicine & Pharmacotherapy 146 (2022) 112513.
https://www.doi.org/10.1016/j.biopha.2021.112513
Violetta Mohos, Zelma Faisal, Eszter Fliszár-Nyúl, Lajos Szente, Miklós Poór, Testing the extraction of 12 mycotoxins from aqueous solutions by insoluble beta-cyclodextrin bead polymer. Environmental Science and Pollution Research 29 (2022) 210-221.
https://www.doi.org/10.1007/s11356-021-15628-1
2021
Imre Vörös, Éva Sághy, Krisztina Pohóczky, András Makkos, Zsófia Onódi, Gábor B. Brenner, Tamás Baranyai, Bence Ágg, Barnabás Váradi, Ágnes Kemény, Przemyslaw Leszek, Anikó Görbe, Zoltán V. Varga, Zoltán Giricz, Rainer Schulz, Zsuzsanna Helyes, Péter Ferdinandy, Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection. Frontiers in Pharmacology 12 (2021) 663655.
https://www.doi.org/10.3389/fphar.2021.663655
Zsolt Csenki, Edina Garai, Zelma Faisal, Rita Csepregi, Kitti Garai, Dóra Kánainé Sipos, István Szabó, Tamás Kőszegi, Árpád Czéh, Tamás Czömpöly, Krisztián Kvell, Miklós Poór, The individual and combined effects of ochratoxin A with citrinin and their metabolites (ochratoxin B, ochratoxin C, and dihydrocitrinone) on 2D/3D cell cultures, and zebrafish embryo models. Food and Chemical Toxicology 158 (2021) 112674.
https://www.doi.org/10.1016/j.fct.2021.112674
Balázs Z. Zsidó, Rita Börzsei, Erika Pintér, Csaba Hetényi, Prerequisite binding modes determine the dynamics of action of covalent agonists of ion channel TRPA1. Pharmaceuticals 14 (2021) 988.
https://www.doi.org/10.3390/ph14100988
Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór, Effects of Microenvironmental Changes on the Fluorescence Signal of Alternariol: Magnesium Induces Strong Enhancement in the Fluorescence of the Mycotoxin. International Journal of Molecular Sciences 22 (2021) 8692.
https://www.doi.org/10.3390/ijms22168692
Balázs Z. Zsidó, Rita Börzsei, Viktor Szél, Csaba Hetényi, Determination of ligand binding modes in hydrated viral ion channels to foster drug design and repositioning. Journal of Chemical Information and Modeling 61 (2021) 4011-4022.
https://www.doi.org/10.1021/acs.jcim.1c00488
Ádám I. Horváth, Nikolett Szentes, Valéria Tékus, Maja Payrits, Éva Szőke, Emőke Oláh, András Garami, Eszter Fliszár-Nyúl, Miklós Poór, Cecília Sár, Tamás Kálai, Szilárd Pál, Krisztina Percze, Éva Nagyné Scholz, Tamás Mészáros, Blanka Tóth, Péter Mátyus, Zsuzsanna Helyes, Proof-of concept for the analgesic effect and thermoregulatory safety of orally administered multi-target compound SZV 1287 in mice: a novel drug candidate for neuropathic pain. Biomedicines 9 (2021) 749.
https://www.doi.org/10.3390/biomedicines9070749
Adrienn Balázs, Zelma Faisal, Rita Csepregi, Tamás Kőszegi, Balázs Kriszt, István Szabó, Miklós Poór, In vitro evaluation of the individual and combined cytotoxic and estrogenic effects of zearalenone, its reduced metabolites, alternariol, and genistein. International Journal of Molecular Sciences 22 (2021) 6281.
https://www.doi.org/10.3390/ijms22126281
Ágnes Dombi, Csenge Sánta, István Z. Bátai, Viktória Kormos, Angéla Kecskés, Valéria Tékus, Krisztina Pohóczky, Kata Bölcskei, Erika Pintér, Gábor Pozsgai, Dimethyl Trisulfide Diminishes Traumatic Neuropathic Pain Acting on TRPA1 Receptors in Mice. International Journal of Molecular Sciences 22 (2021) 3363.
https://www.doi.org/10.3390/ijms22073363
Eszter Fliszár-Nyúl, Zelma Faisal, Violetta Mohos, Diána Derdák, Beáta Lemli, Tamás Kálai, Cecília Sár, Balázs Z. Zsidó, Csaba Hetényi, Ádám I. Horváth, Zsuzsanna Helyes, Ruth Deme, Dóra Bogdán, Andrea Czompa, Péter Mátyus, Miklós Poór, Interaction of SZV 1287, a novel oxime analgesic drug candidate, and its metabolites with serum albumin. Journal of Molecular Liquids 333 (2021) 115945.
https://www.doi.org/10.1016/j.molliq.2021.115945
Zelma Faisal, Violetta Mohos, Eszter Fliszár-Nyúl, Kateřina Valentová, Kristýna Káňová, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór, Interaction of silymarin components and their sulfate metabolites with human serum albumin and cytochrome P450 (2C9, 2C19, 2D6, and 3A4) enzymes. Biomedicine & Pharmacotherapy 138 (2021) 111459.
https://www.doi.org/10.1016/j.biopha.2021.111459
Gábor Kriszta, Zsófia Kriszta, Szilárd Váncsa, Péter J. Hegyi, Levente Frim, Bálint Erőss, Péter Hegyi, Gábor Pethő, Erika Pintér, Effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on angiotensin-converting enzyme 2 levels: a comprehensive analysis based on animal studies. Frontiers in Pharmacology 12 (2021) 619524.
https://www.doi.org/10.3389/fphar.2021.619524
Boglárka Kántás, Éva Szőke, Rita Börzsei, Péter Bánhegyi, Junaid Asghar, Lina Hudhud, Anita Steib, Ágnes Hunyady, Ádám Horváth, Angéla Kecskés, Éva Borbély, Csaba Hetényi, Gábor Pethő, Erika Pintér, Zsuzsanna Helyes, In Silico, In Vitro and In Vivo Pharmacodynamic Characterization of Novel Analgesic Drug Candidate Somatostatin SST4 Receptor Agonists. Frontiers in Pharmacology 11 (2021) 601887.
https://www.doi.org/10.3389/fphar.2020.601887
Éva Borbély, Ágnes Hunyady, Krisztina Pohóczky, Maja Payrits, Bálint Botz, Attila Mócsai, Alexandra Berger, Éva Szőke, Zsuzsanna Helyes, Hemokinin-1 as a Mediator of Arthritis-Related Pain via Direct Activation of Primary Sensory Neurons. Frontiers in Pharmacology 11 (2021) 594479.
https://www.doi.org/10.3389/fphar.2020.594479
2020
Angéla Kecskés, Krisztina Pohóczky, Miklós Kecskés, Zoltán V. Varga, Viktória Kormos, Éva Szőke, Nóra Henn-Mike, Máté Fehér, József Kun, Attila Gyenesei, Éva Renner, Miklós Palkovits, Péter Ferdinándy, István M. Ábrahám, Balázs B. Gaszner, Zsuzsanna Helyes, Characterization of neurons expressing the novel analgesic drug target somatostatin receptor 4 in mouse and human brains. International Journal of Molecular Sciences 21 (2020) 7788.
https://www.doi.org/10.3390/ijms21207788
Eszter Fliszár-Nyúl, Violetta Mohos, Rita Csepregi, Přemysl Mladěnka, Miklós Poór, Inhibitory effects of polyphenols and their colonic metabolites on CYP2D6 enzyme using two different substrates. Biomedicine & Pharmacotherapy 131 (2020) 110732.
https://www.doi.org/10.1016/j.biopha.2020.110732
Eszter Fliszár-Nyúl, Ákos Szabó, Lajos Szente, Miklós Poór, Extraction of mycotoxin alternariol from red wine and from tomato juice with beta-cyclodextrin bead polymer. Journal of Molecular Liquids 319 (2020) 114180.
https://www.doi.org/10.1016/j.molliq.2020.114180
Zelma Faisal, Virág Vörös, Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór, Interactions of zearalanone, α-zearalanol, β-zearalanol, zearalenone-14-sulfate, and zearalenone-14-glucoside with serum albumin. Mycotoxin Research 36 (2020) 389–397.
https://www.doi.org/10.1007/s12550-020-00404-w
Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Katalin Kuffa, Paul W. Needs, Paul A. Kroon, Ágnes Telbisz, Csilla Özvegy-Laczka, Miklós Poór, Inhibitory effects of quercetin and its main methyl, sulfate, and glucuronic acid conjugates on cytochrome P450 enzymes, and on OATP, BCRP and MRP2 transporters. Nutrients 12 (2020) 2306.
https://www.doi.org/10.3390/nu12082306
Maja Payrits, Ádám Horváth, Tünde Biró-Sütő, János Erostyák, Géza Makkai, Éva Sághy, Krisztina Pohóczky, Angéla Kecskés, Miklós Kecskés, János Szolcsányi, Zsuzsanna Helyes, Éva Szőke, Resolvin D1 and D2 Inhibit Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Ion Channel Activation on Sensory Neurons via Lipid Raft Modification. International Journal of Molecular Sciences 21 (2020) 5019.
https://www.doi.org/10.3390/ijms21145019
Fruzsina Kiss, Krisztina Pohóczky, Árpád Szállási, Zsuzsanna Helyes, Transient Receptor Potential (TRP) Channels in Head-and-Neck Squamous Cell Carcinomas: Diagnostic, Prognostic, and Therapeutic Potentials. International Journal of Molecular Sciences 21 (2020) 6374.
https://www.doi.org/10.3390/ijms21176374
Violetta Mohos, Eszter Fliszár-Nyúl, Orsolya Ungvári, Éva Bakos, Katalin Kuffa, Tímea Bencsik, Balázs Zoltán Zsidó, Csaba Hetényi, Ágnes Telbisz, Csilla Özvegy-Laczka, Miklós Poór, Effects of chrysin and its major conjugated metabolites chrysin-7-sulfate and chrysin-7-glucuronide on cytochrome P450 enzymes, and on OATP, P-gp, BCRP and MRP2 transporters. Drug Metabolism and Disposition 48 (2020) 1064–1073.
https://www.doi.org/10.1124/dmd.120.000085
Zelma Faisal, Virág Vörös, Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Rita Csepregi, Tamás Kőszegi, Ferenc Zsila, Miklós Poór, Probing the interactions of ochratoxin B, ochratoxin C, patulin, deoxynivalenol, and T-2 toxin with human serum albumin. Toxins 12 (2020) 392.
https://www.doi.org/10.3390/toxins12060392
Zelma Faisal, Eszter Fliszár-Nyúl, Luca Dellafiora, Gianni Galaverna, Chiara Dall’Asta, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Miklós Poór, Interaction of zearalenone-14-sulfate with cyclodextrins and the removal of the modified mycotoxin from aqueous solution by beta-cyclodextrin bead polymer. Journal of Molecular Liquids 310 (2020) 113236.
https://www.doi.org/10.1016/j.molliq.2020.113236
Violetta Mohos, Eszter Fliszár-Nyúl, Miklós Poór, Inhibition of xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation by flavonoid aglycones and some of their conjugates. International Journal of Molecular Sciences 21 (2020) 3256.
https://www.doi.org/10.3390/ijms21093256
Violetta Mohos, Eszter Fliszár-Nyúl, Beáta Lemli, Balázs Z. Zsidó, Csaba Hetényi, Přemysl Mladěnka, Pavel Horký, Milan Pour, Miklós Poór, Testing the pharmacokinetic interactions of 24 colonic flavonoid metabolites with human serum albumin and cytochrome P450 enzymes. Biomolecules 10 (2020) 409.
https://www.doi.org/10.3390/biom10030409
Zelma Faisal, Edina Garai, Rita Csepregi, Katalin Bakos, Eszter Fliszár-Nyúl, Lajos Szente, Adrienn Balázs, Mátyás Cserháti, Tamás Kőszegi, Béla Urbányi, Zsolt Csenki, Miklós Poór, Protective effects of beta-cyclodextrins vs. zearalenone-induced toxicity in HeLa cells and Tg(vtg1:mCherry) zebrafish embryos. Chemosphere 240 (2020) 124948.
https://www.doi.org/10.1016/j.chemosphere.2019.124948
Balázs Z. Zsidó, Mária Balog, Nikolett Erős, Miklós Poór, Violetta Mohos, Eszter Fliszár-Nyúl, Csaba Hetényi, Masaki Nagane, Kálmán Hideg, Tamás Kálai, Balázs Bognár, Synthesis of Spin-Labelled Bergamottin: A Potent CYP3A4 Inhibitor with Antiproliferative Activity. International Journal of Molecular Sciences 21 (2020) 508.
https://www.doi.org/10.3390/ijms21020508
K. Pohóczky, A. Tamás, D. Reglődi, A. Kemény, Zs. Helyes, L. Czeglédi, Pituitary adenylate cyclase activating polypeptide concentrations in the sheep mammary gland, milk, and in the lamb blood plasma after suckling. Physiology International 107 (2020) 92-105.
https://www.doi.org/10.1556/2060.2020.00006
2019
Eszter Fliszár-Nyúl, Violetta Mohos, Tímea Bencsik, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór, Interactions of 7,8-dihydroxyflavone with serum albumin as well as with CYP2C9, CYP2C19, CYP3A4, and xanthine oxidase biotransformation enzymes. Biomolecules 9 (2019) 655.
https://www.doi.org/10.3390/biom9110655
Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Miklós Poór, Interactions of mycotoxin alternariol with cyclodextrins and its removal from aqueous solution by beta-cyclodextrin bead polymer. Biomolecules 9 (2019) 428.
https://www.doi.org/10.3390/biom9090428
Zelma Faisal, Eszter Fliszár-Nyúl, Luca Dellafiora, Gianni Galaverna, Chiara Dall’Asta, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Miklós Poór, Cyclodextrins can entrap zearalenone-14-glucoside: Interaction of the masked mycotoxin with cyclodextrins and cyclodextrin bead polymer. Biomolecules 9 (2019) 354.
https://www.doi.org/10.3390/biom9080354
Zelma Faisal, Sándor Kunsági-Máté, Beáta Lemli, Lajos Szente, Dominik Bergmann, Hans-Ulrich Humpf, Miklós Poór, Interaction of dihydrocitrinone with native and chemically modified cyclodextrins. Molecules 24 (2019) 1328.
https://www.doi.org/10.3390/molecules24071328
Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Luca Dellafiora, Chiara Dall'Asta, Gabriele Cruciani, Gábor Pethő, Miklós Poór, Interaction of mycotoxin alternariol with serum albumin. International Journal of Molecular Sciences 20 (2019) 2352.
https://www.doi.org/10.3390/ijms20092352
Violetta Mohos, Attila Pánovics, Eszter Fliszár-Nyúl, Gabriella Schilli, Csaba Hetényi, Přemysl Mladěnka, Paul W. Needs, Paul A. Kroon, Gábor Pethő, Miklós Poór, Inhibitory effects of quercetin and its human and microbial metabolites on xanthine oxidase enzyme. International Journal of Molecular Sciences 20 (2019) 2681.
https://www.doi.org/10.3390/ijms20112681
Róbert György Vida, András Fittler, Anna Somogyi-Végh, Miklós Poór, Dietary quercetin supplements: assessment of online product informations and quantitation of quercetin in the products by high performance liquid chromatography. Phytotherapy Research 33 (2019) 1912-1920.
https://www.doi.org/10.1002/ptr.6382
Zelma Faisal, Virág Vörös, Beáta Lemli, Diána Derdák, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Rita Csepregi, Tamás Kőszegi, Dominik Bergmann, Franziska Sueck, Hans-Ulrich Humpf, Florian Hübner, Miklós Poór, Interaction of the mycotoxin metabolite dihydrocitrinone with serum albumin. Mycotoxin Research 35 (2019) 129-139.
https://www.doi.org/10.1007/s12550-018-0336-z
Diána Derdák, Miklós Poór, Sándor Kunsági-Máté, Beáta Lemli, Interaction of amphotericin B with human and bovine serum albumins: A fluorescence polarization study. Chemical Physics Letters 724 (2019) 13-17.
https://www.doi.org/10.1016/j.cplett.2019.03.049
Hiba Mohamed Ameen, Sándor Kunsági-Máté, Balázs Bognár, Lajos Szente, Miklós Poór, Beáta Lemli, Thermodynamic characterization of the interaction between the antimicrobial drug sulfamethazine and two selected cyclodextrins. Molecules 24 (2019) 4565.
https://www.doi.org/10.3390/molecules24244565
Zsuzsanna Helyes, Valéria Tékus, Nikolett Szentes, Krisztina Pohóczky, Bálint Botz, Tamás Kiss, Ágnes Keménya, Zsuzsanna Környei, Krisztina Tóth, Nikolett Lénárt, Hajnalka Ábrahám, Emmanuel Pinteaux, Sheila Francis, Serena Sensi, Ádám Dénes, Andreas Goebel, Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin1–induced mechanisms. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (2019) 13067-13076.
https://www.doi.org/10.1073/pnas.1820168116
Nikolett Szentes, Valéria Tékus, Violetta Mohos, Éva Borbély, Zsuzsanna Helyes, Exploratory and locomotor activity, learning and memory functions in somatostatin receptor subtype 4 gene-deficient mice in relation to aging and sex. Geroscience 116 (2019) 13067–13076.
https://www.doi.org/10.1007/s11357-019-00059-1
Eszter Ducza, Adrienn Csányi, Éva Szőke, Krisztina Pohóoczky, Judit Hajagos-Tóth, Anna Kothencz, Zita Tiszai, Róbert Gáspár, Significance of transient receptor potential vanilloid 4 and aquaporin 5 co-expression in the rat uterus at term. Heliyon 5 (2019) e02697.
https://www.doi.org/10.1016/j.heliyon.2019.e02697
Boglárka Kántás, Rita Börzsei, Éva Szőke, Péter Bánhegyi, Ádám Horváth, Ágnes Hunyady, Éva Borbély, Csaba Hetényi, Erika Pintér, Zsuzsanna Helyes, Novel Drug-Like Somatostatin Receptor 4 Agonists are Potential Analgesics for Neuropathic Pain. International Journal of Molecular Sciences 20 (2019) 6245.
https://www.doi.org/10.3390/ijms20246245
2018
Nikolett Sali, Rita Csepregi, Tamás Kőszegi, Sándor Kunsági-Máté, Lajos Szente, Miklós Poór, Complex formation of flavonoids fisetin and geraldol with β-cyclodextrins. Journal of Luminescence 194 (2018) 82-90.
https://www.doi.org/10.1016/j.jlumin.2017.10.017
Miklós Poór, Gabriella Boda, Sándor Kunsági-Máté, Paul W. Needs, Paul A. Kroon, Beáta Lemli, Fluorescence spectroscopic evaluation of the interactions of quercetin, isorhamnetin, and quercetin-3'-sulfate with different albumins. Journal of Luminescence 194 (2018) 156-163.
https://www.doi.org/10.1016/j.jlumin.2017.10.024
Rita Csepregi, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Tamás Kőszegi, Balázs Németi, Miklós Poór, Complex formation of resorufin and resazurin with β-cyclodextrins: Can cyclodextrins interfere with a resazurin cell viability assay? Molecules 23 (2018) 382.
https://www.doi.org/10.3390/molecules23020382
Miklós Poór, Gabriella Boda, Violetta Mohos, Mónika Kuzma, Mónika Bálint, Csaba Hetényi, Tímea Bencsik, Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin. Biomedicine & Pharmacotherapy 102 (2018) 912-921.
https://www.doi.org/10.1016/j.biopha.2018.03.146
Miklós Poór, Zelma Faisal, Afshin Zand, Tímea Bencsik, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Removal of zearalenone and zearalenols from aqueous solutions using insoluble beta-cyclodextrin bead polymer. Toxins 10 (2018) 216.
https://www.doi.org/10.3390/toxins10060216
Franziska Sueck, Miklós Poór, Zelma Faisal, Christoph G.W. Gertzen, Benedikt Cramer, Beáta Lemli, Sándor Kunsági-Máté, Holger Gohlke, Hans-Ulrich Humpf, Interaction of ochratoxin A and its thermal degradation product 2’R-ochratoxin A with human serum albumin. Toxins 10 (2018) 256.
https://www.doi.org/10.3390/toxins10070256
Rita Csepregi, Viktória Temesfői, Miklós Poór, Zsuzsanna Faust, Tamás Kőszegi, Green Fluorescent Protein-based viability assay in a multipara-metric configuration. Molecules 23 (2018) 1575.
https://www.doi.org/10.3390/molecules23071575
Zelma Faisal, Beáta Lemli, Dénes Szerencsés, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Mónika Kuzma, Mátyás Mayer, Miklós Poór, Interactions of zearalenone and its reduced metabolites α-zearalenol and β-zearalenol with serum albumins: species differences, binding sites, and thermodynamics. Mycotoxin Research 34 (2018) 269-278.
https://www.doi.org/10.1007/s12550-018-0321-6
Violetta Mohos, Tímea Bencsik, Gabriella Boda, Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór, Interactions of casticin, ipriflavone, and resveratrol with serum albumin and their inhibitory effects on CYP2C9 and CYP3A4 enzymes. Biomedicine & Pharmacotherapy 107 (2018) 777-784.
https://www.doi.org/10.1016/j.biopha.2018.08.068
Zelma Faisal, Diána Derdák, Beáta Lemli, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Rita Csepregi, Tamás Kőszegi, Franziska Sueck, Hans-Ulrich Humpf, Benedikt Cramer, Miklós Poór, Interaction of 2'R-ochratoxin A with serum albumins: Binding site, effects of site markers, thermodynamics, species differences of albumin-binding, and influence of albumin on its toxicity in MDCK cells. Toxins 10 (2018) 353.
https://www.doi.org/10.3390/toxins10090353
Rita Csepregi, Viktória Temesfői, Nikolett Sali, Miklós Poór, Paul W. Needs, Paul A. Kroon, Tamás Kőszegi, A one-step extraction and luminescence assay for quantifying glucose and ATP levels in cultured HepG2 cells. International Journal of Molecular Sciences 19 (2018) 2670.
https://www.doi.org/10.3390/ijms19092670
Violetta Mohos, Eszter Fliszár-Nyúl, Gabriella Schilli, Csaba Hetényi, Beáta Lemli, Sándor Kunsági-Máté, Balázs Bognár, Miklós Poór, Interaction of chrysin and its main conjugated metabolites chrysin-7-sulfate and chrysin-7-glucuronide with serum albumin. International Journal of Molecular Sciences 19 (2018) 4073.
https://www.doi.org/10.3390/ijms19124073
2017
Miklós Poór, Afshin Zand, Lajos Szente, Beáta Lemli, Sándor Kunsági-Máté, Interaction of α- and β-zearalenols with β-cyclodextrins. Molecules 22 (2017) 1910.
https://www.doi.org/10.3390/molecules22111910
Miklós Poór, Mónika Bálint, Csaba Hetényi, Beatrix Gődér, Sándor Kunsági-Máté, Tamás Kőszegi, Beáta Lemli, Investigation of non-covalent interactions of aflatoxins (B1, B2, G1, G2, and M1) with serum albumin. Toxins 9 (2017) 339.
https://www.doi.org/10.3390/toxins9110339
Tamás Kőszegi, Nikolett Sali, Maja Raknić, Zoltán Horváth-Szalai, Rita Csepregi, Marijana Zovko Končić, Nóra Papp, Miklós Poór, A novel luminol-based enhanced chemiluminescence antioxidant capacity microplate assay for use in different biological matrices. Journal of Pharmacological and Toxicological Methods 88 (2017) 153-159.
https://www.doi.org/10.1016/j.vascn.2017.09.256
Miklós Poór, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Zsófia Gerner, Beáta Lemli, Interaction of mycotoxin zearalenone with human serum albumin. Journal of Photochemistry and Photobiology B: Biology 170 (2017) 16-24.
https://www.doi.org/10.1016/j.jphotobiol.2017.03.016
Miklós Poór, Gabriella Boda, Paul W Needs, Paul A Kroon, Beáta Lemli, Tímea Bencsik, Interaction of quercetin and its metabolites with warfarin: Displacement of warfarin from serum albumin and inhibition of CYP2C9 enzyme. Biomedicine & Pharmacotherapy 88 (2017) 574-581.
https://www.doi.org/10.1016/j.biopha.2017.01.092
Miklós Poór, Balázs Németi, Zoltán Gregus, Effects of phosphate binders on the gastrointestinal absorption of arsenate and of an SGLT2 inhibitor drug on the urinary excretion of arsenite in mice. Environmental Toxicology and Pharmacology 49 (2017) 179-187.
https://www.doi.org/10.1016/j.etap.2017.01.002
2016
Miklós Poór, Gergely Matisz, Sándor Kunsági-Máté, Diána Derdák, Lajos Szente, Beáta Lemli, Fluorescence spectroscopic investigation of the interaction of citrinin with native and chemically modified cyclodextrins. Journal of Luminescence 172 (2016) 23-28.
https://www.doi.org/10.1016/j.jlumin.2015.11.011
Miklós Poór, Zita Zrínyi, Tamás Kőszegi, Structure related effects of flavonoid aglycones on cell cycle progression of HepG2 cells: Metabolic activation of fisetin and quercetin by catechol-O-methyltransferase (COMT). Biomedicine & Pharmacotherapy 83 (2016) 998-1005.
https://www.doi.org/10.1016/j.biopha.2016.08.009
Tamás Kőszegi, Miklós Poór, Ochratoxin A: Molecular interactions, mechanisms of toxicity and prevention at the molecular level. Toxins 8 (2016) 111.
https://www.doi.org/10.3390/toxins8040111
Nikolett Sali, Miklós Poór, Sándor Nagy, Tamás Kőszegi, Multiparametric luminescent cell viability assay in toxicology models: a critical evaluation. Journal of Pharmacological and Toxicological Methods 79 (2016) 45-54.